Cell Line Lysates
ABclonal Technology IL18 Rabbit PolymAb
by caspase-1 and is capable of stimulating interferon gamma production and of regulating both T helper (Th) 1 and Th2 responses This cytokine has been implicated in the injury of different organs and in potentially fatal conditions characterized by a cytokine storm In humans IL-18 gene is located on chromosome 11 Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Rockland Immunochemicals U-87MG Whole Cell Lysate 500µg
Ready-to-use lysates are especially prepared as positive controls for separation by SDS-PAGE and subsequent western blot analysis. Lysates are prepared in denaturing buffer WITHOUT dissociating agents (i.e. no 2-mercaptoethanol or dithiothreitol has been added). Heat lysate to 95° C for 5 minutes and rapidly cool. If dissociating conditions are desired, add reducing agent prior to heating. The recommended loading volume per lane is 10-20 µL depending on the size format of your gel.
Abcam Human DSG2 (Desmoglein 2) knockout A549 cell lysate.
Human DSG2 (Desmoglein 2) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Biochain Institute Inc Total Protein - hypertension: Heart Ventricle, left, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
Biotium Beta Catenin (p120)(Rabbit PAb), CF740 conjugate, 0.1mg/mL
Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other
Cayman Chemical AscochlorIn 2.5mg
An isoprenoid antibiotic and antiviral that suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 µM) by inhibiting the expression of MMP-9; profoundly increases the expression of p53 by increasing protein stability in cancer cells and inhibits signaling through STAT3
Abcam Human GLRX2 (GRX2) knockout HeLa cell lysate.
Human GLRX2 (GRX2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Scopulaops F244 ymglusn 2.5mg
A fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme; targets cell walls of pathogens such as S. aureus in a mouse sepsis model of infection
ABclonal Technology SRD5A1 Rabbit pAb
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).
Cayman Chemical LSelectInCD62L EXrAClula 200ug
Source: Recombinant human C-terminal His-tagged L-selectin expressed in CHO cells • Amino acids: 29-332 • MW: 35.6 kDa
Cayman Chemical SCH 38519 2.5mg
A fungal metabolite; inhibits thrombin-induced aggregation, as well as inhibits serotonin secretion in human platelets (IC50s = 68 and 61 UG/ml, respectively); inhibits the growth of various Gram-negative and Gram-positive bacteria (mean MICs = 122.1 and 0.92 UG/ml, respectively)
Eurofins Discoverx InCELL Hunter™ Human G9a Methyltransferase Target Engagement Cell-Based Assay Kit (A549)
The InCELL Hunter™ Human G9a Stable Cell Line Target Engagement Assay (A549) contains a stable clonal cell line used to measure target engagement via compound-induced stabilization of G9a target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical 7hydroxy CLOrpromazInhyd 2.5mg
An active metabolite of chlorpromazine; increases plasma prolactin levels in male rats at 5 mg/kg; reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats at 1.6 mg/kg